Anaesthesia, Pain, Intensive Care and Emergency A.P.I.C.E.: by C. S. N. B. Garcia, P. R. M. Rocco, M. M. Morales (auth.),

By C. S. N. B. Garcia, P. R. M. Rocco, M. M. Morales (auth.), Antonino Gullo M.D. (eds.)

Development within the box of medication over the past 50 years has ended in very important effects for society, either by way of prevention and within the remedy of unmarried or variously linked pathologies. the most aim of recent medication has been the purchase of elevated talents and hugely specialized wisdom within the a number of disciplines. while, there was a innovative multidisciplinary and multi-professional curiosity in acute disorder stipulations that position the sufferer in strength or genuine life-threatening occasions. The state-of-the-art of in depth drugs contains a variety of subtle interventions and collaboration among assorted scientific disciplines, either one of which provide the sufferer entry to the main complicated different types of therapy which are at present to be had.

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Extra resources for Anaesthesia, Pain, Intensive Care and Emergency A.P.I.C.E.: Proceedings of the 20th Postgraduate Course in Critical Care Medicine Trieste, Italy — November 18–21, 2005

Example text

Nonetheless, the impact on medicine of all these discoveries has been minimal, although scientists continue to predict that molecular biology will dominate clinical studies and revolutionise their present concepts and treatment strategies. Molecular biology is sustained by the concept that all living creatures depend on the production of proteins codified by genes contained within DNA. The genes are transcribed into messenger ribonucleic acid (mRNA) by a RNA polymerase that binds to DNA at a nucleotide promoter sequence, located in close proximity to the gene.

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76. 77. 78. 79. 80. 81. 82. 83. 84. 85. 86. 87. 88. 89. 90. B. M. M. Morales trix interactions of human fibroblasts and endothelial cells in vitro. J Cell Sci 109:479–488 Vlahakis NE, Schroeder MA, Limper AH et al (1999) Stretch induces cytokine release by alveolar epithelial cells in vitro. Am J Physiol 277:L167–L173 Oudin S, Pugin J (2002) Role of MAP kinase activation in interleukin-8 production by human BEAS-2B bronchial epithelial cells submitted to cyclic stretch. Am J Respir Cell Mol Biol 27:107–114 Li LF, Ouyang B, Choukroun G et al (2003) Stretch-induced IL-8 depends on c-Jun NH2-terminal and nuclear factor-kB-inducing kinases.

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