By Kian Fan Chung
During this ebook, top researchers in medication and molecular pharmacology clarify the mobile mechanisms that regulate airway soft muscle. The skill through which those are disrupted in affliction, and the pharmacologic innovations through which they're changed are mentioned and destiny healing interventions are identified. Aimed at experts in pulmonology, this quantity presents the clinician with the hottest details on one of many center physiological methods in airway affliction, and provides insights into present and destiny methods to management. Authoritative replace on key mechanisms of airway constriction in bronchial asthma and COPDRelates most up-to-date examine to bronchodilator therapyMulti-contributed textual content, co-coordinated via of the major gurus within the box.
Read Online or Download Airway Smooth Muscle in Asthma and COPD: Biology and Pharmacology PDF
Similar pulmonary & thoracic medicine books
This quantity within the robot Radiosurgery sequence is dedicated to the idea and perform within the rising box of stereotactic radiosurgery for extracranial tumors, fairly those who movement as sufferers breathe. distinctive consciousness is given to the frameless robot radiosurgery gadget often called the CyberKnife.
Can the military successfully enforce scientific remedy instructions in its army remedy amenities to accomplish constant and hig h caliber practices thoughout its future health procedure?
Pulmonary emphysema is a disorder which develops due to a localized imbalance among endogenous proteinase inhibitors and proteinases leaking from neurophils in the course of phagocytosis at inflammatory foci in the lung. This quantity not just studies at a biochemical point what's recognized concerning the usual inhibitors and proteinases concerned with connective tissue destruction in the lung, but in addition indicates novel methodologies for reestablishing right enzyme-inhibitor stability, together with using synthetic or natural inhibitors for supplementation or gene remedy.
This booklet is a crucial new source for clinicians taking care of ventilator based childrens, who frequently have complicated well-being care wishes, are supported by means of complicated expertise and are at high-risk of significant problems. regardless of the complex overall healthiness care wishes of kids who depend on continual breathing help, there are few instructions and little facts to be had to lead the clinicians who take care of those sufferers.
- Injuries to the Chest Wall: Diagnosis and Management
- Clinical Tuberculosis (A Hodder Arnold Publication) - 4th edition
- Community-Acquired Respiratory Infections (Infectious Disease and Therapy)
- Nunn's Applied Respiratory Physiology
Additional info for Airway Smooth Muscle in Asthma and COPD: Biology and Pharmacology
1992). A model of airway narrowing in asthma and in chronic obstructive pulmonary disease. Am Rev Respir Dis 145, 1251–1258. Wiggs, B. , Hrousis, C. , Drazen, J. M. et al. (1997). On the mechanism of mucosal folding in normal and asthmatic airways. J Appl Physiol 83, 1814–1821. Woodruff, P. , Dolganov, G. , Ferrando, R. E. et al. (2004). Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression. Am J Respir Crit Care Med 169, 1001–1006. Woolcock, A.
Ford, L. , Seow, C. Y. and Pratusevich, V. R. (1994). Plasticity in smooth muscle, a hypothesis. Can J Physiol Pharmacol 72, 1320–1324. Fredberg, J. J. (1998). Airway smooth muscle in asthma: flirting with disaster. Eur Respir J 12, 1252–1256. Fredberg, J. J. (2000a). Airway smooth muscle in asthma. Perturbed equilibria of myosin binding. Am J Respir Crit Care Med 161, S158–S160. Fredberg, J. J. (2000b). Frozen objects: small airways, big breaths, and asthma. J Allergy Clin Immunol 106, 615–624.
Endogenous laminin is required for human airway smooth muscle cell maturation. Respir Res 7, 117. S. , (2007). Universal physical responses to stretch in the living cell. Nature 447, 592–595. Tschumperlin, D. , Shively, J. , Swartz, M. A. et al. (2002). Bronchial epithelial compression regulates MAP kinase signaling and HB-EGF-like growth factor expression. Am J Physiol 282, L904–L911. Tschumperlin, D. , Shively, J. , Kikuchi, T. et al. (2003). Mechanical stress triggers selective release of fibrotic mediators from bronchial epithelium.