Airway Smooth Muscle in Asthma and COPD: Biology and by Kian Fan Chung

By Kian Fan Chung

During this ebook, top researchers in medication and molecular pharmacology clarify the mobile mechanisms that regulate airway soft muscle. The skill through which those are disrupted in affliction, and the pharmacologic innovations through which they're changed are mentioned and destiny healing interventions are identified. Aimed at experts in pulmonology, this quantity presents the clinician with the hottest details on one of many center physiological methods in airway affliction, and provides insights into present and destiny methods to management. Authoritative replace on key mechanisms of airway constriction in bronchial asthma and COPDRelates most up-to-date examine to bronchodilator therapyMulti-contributed textual content, co-coordinated via of the major gurus within the box.

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1992). A model of airway narrowing in asthma and in chronic obstructive pulmonary disease. Am Rev Respir Dis 145, 1251–1258. Wiggs, B. , Hrousis, C. , Drazen, J. M. et al. (1997). On the mechanism of mucosal folding in normal and asthmatic airways. J Appl Physiol 83, 1814–1821. Woodruff, P. , Dolganov, G. , Ferrando, R. E. et al. (2004). Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression. Am J Respir Crit Care Med 169, 1001–1006. Woolcock, A.

Ford, L. , Seow, C. Y. and Pratusevich, V. R. (1994). Plasticity in smooth muscle, a hypothesis. Can J Physiol Pharmacol 72, 1320–1324. Fredberg, J. J. (1998). Airway smooth muscle in asthma: flirting with disaster. Eur Respir J 12, 1252–1256. Fredberg, J. J. (2000a). Airway smooth muscle in asthma. Perturbed equilibria of myosin binding. Am J Respir Crit Care Med 161, S158–S160. Fredberg, J. J. (2000b). Frozen objects: small airways, big breaths, and asthma. J Allergy Clin Immunol 106, 615–624.

Endogenous laminin is required for human airway smooth muscle cell maturation. Respir Res 7, 117. S. , (2007). Universal physical responses to stretch in the living cell. Nature 447, 592–595. Tschumperlin, D. , Shively, J. , Swartz, M. A. et al. (2002). Bronchial epithelial compression regulates MAP kinase signaling and HB-EGF-like growth factor expression. Am J Physiol 282, L904–L911. Tschumperlin, D. , Shively, J. , Kikuchi, T. et al. (2003). Mechanical stress triggers selective release of fibrotic mediators from bronchial epithelium.

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